When we are as a manufacturer that produce so many kinds of stuff for market, there is a rule that we must determine the time line of our products. Like when the first time we decide when our product will be launched in the market, we should know when we supposed to be stopping produce our product and let the rest absorb and disappear from the market. This is look like complex period and system but for the research team, this their daily breakfast so let their information guide your decision.
But before you cut off the distribution of product, you should prepare new variant as a replacement of the existing, so there is small overlapping and smooth transition. For example your company produce weight loss supplement and you look the market already resistant with the current variant so you have to develop new variant base on weight loss supplements reviews and demand in the market. The time line of product development should be as short as possible so the new product can be launched at the right time.